P53, bcl-2, and nm23 expressions in serous ovarian tumors: correlation with the clinical and histopathological parameters

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p53, bcl-2, and nm23 Expressions in Serous Ovarian Tumors: Correlation with the Clinical and Histopathological Parameters Seröz Over Tümörlerinde p53, bcl-2 ve nm23 Ekspresyonu: Klinik ve Histopatolojik Parametreler ile İlişkisi

Objective: We studied p53, bcl-2, and nm23 expressions in serous benign, borderline and malignant tumors of the ovary. Our aim was to determine the association between these expressions and some clinical (patient age, tumor dimension, omenthal involvement, the presence of malignant cells in peritoneal fluid) and histopathological (grade, number of mitosis, nuclear pleomorphism, structural patte...

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Immunohistochemical Expression of CD44V6, P53 and BCL-2 in Epithelial Ovarian Tumors

Ovarian epithelial cancer is a leading cause of death among gynaecological malignancies due mainly to advanced stage at presentation. Aim of the work: The purpose of this study was to investigate the expression and prognostic significance of CD44v6, Bcl-2 and P53 in ovarian tumors of low malignant potential (LMP) and primary epithelial ovarian carcinomas Experimental Design: We analyzed the imm...

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estrogen and progesterone receptor expression and its correlation with various clinicopathological parameters in ovarian tumors

background : this study evaluates estrogen and progesterone expressions in patients with ovarian tumors (both benign and malignant) and their correlation with various clinicopathological prognostic parameters. receptors for estrogen and progesterone are predictive and prognostic markers of endometrial and breast cancers. however, their clinical significance in epithelial ovarian cancer is not c...

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The study of p53 and p16 immunoexpression in serous borderline and malignant ovarian tumors.

The study assessed p53 and p16 immunoexpression in 20 cases of ovarian serous carcinomas and four cases of serous borderline tumors, the results being statistically analyzed in relation to clinicopathological data of the cases. The p53 immunoreaction was observed in 85% of cases, the medium percentage of positivity being 15% for borderline tumors, 45% for low-grade carcinomas and 60% for high-g...

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ژورنال

عنوان ژورنال: Turkish Journal of Pathology

سال: 2011

ISSN: 1018-5615,1309-5730

DOI: 10.5146/tjpath.2011.01010